Kimbler Lecture Series Featuring Dr.Binil Starly
"Manufacturing for Regenerative Medicine"
Binil Starly, PhD
Dr. Binil Starly is currently appointed as an Associate Professor in the Industrial and Systems Engineering at North Carolina State University (NCSU). He directs the Laboratory for Engineered Tissue Systems Manufacturing engaged in Tissue bioprocessing for Regenerative Medicine therapies and in-vitro drug screening systems. He has received the National Science Foundation CAREER award for research in engineering living tissue systems. He has published over 28 journal publications and awarded 1 US Patent in the field of design/manufacturing, customized biomedical implants and tissue model systems. His research activities can be found at http://www.tissuemfg.org
Engineered tissue systems have applications in regenerative medicine, pre-clinical models for drug-screening, models to study disease pathology and non-therapeutic applications such as tissue based sensors. For the eventual implantation of engineered tissue and organs, manufacturing platforms for engineered tissue has been identified as a critical enabling technology essential to translate laboratory intensive tissue engineering procedures to a scalable economically viable process. As manufacturing engineers, we must address the fundamental challenge – ‘How do we engineer the complex human tissue biology for adequate structural stability, uniform product quality and high standards of functional assurance’. Over the past 7 years, our laboratory has sought to address this challenge by developing core competencies in porous scaffold fabrication, cell encapsulated printed hydrogels, real-time oxygen sensing, impedance spectroscopy and bioreactor systems. The presentation will specifically address:-1) Porous metallic and polymer scaffold fabrication for regenerative medicine; 2) 3D In vitro tissue models for next-generation drug screening; 3) Adult stem cell characterization by measuring its dielectric properties; and 4) The next decade of research into the scale-up production platforms for engineered tissue applications.
Interactive session and Refreshments will be served at 12:00-1:30 PM in ENC 2407